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AbbVie's Maviret (glecaprevir/pibrentasvir) Receives European Commission Approval for Treatment-Naive Patients with Chronic Hepatitis C and Compensated Cirrhosis

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AbbVie's Maviret (glecaprevir/pibrentasvir) Receives European Commission Approval for Treatment-Naive Patients with Chronic Hepatitis C and Compensated Cirrhosis

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  • The marketing authorization is based on P-IIIb EXPEDITION-8 study assessing Maviret in 280 treatment-naive chronic HCV patients with compensated cirrhosis across all major genotypes (GT1-6) for 8wks.
  • The P-IIIb EXPEDITION-8 study resulted in @8wks. 97.9% GT1- 2- 4- 5 & 6 patients achieved a sustained virologic response 12wks. (SVR12); no case of virologic failures and discontinued treatment were observed
  • Maviret is a combination of NS3/4A protease & NS5A inhibitor and is an 8-week- pan-genotypic option (GT1-6) for patients who are new to treatment and without cirrhosis and for GT1- 2- 4- 5 and 6 patients who are new to treatment with compensated cirrhosis

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Ref: AbbVie | Image:AbbVie


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