Shots:

• The approval is based on P-IIIb EXPEDITION-8 study assessing Maviret in 343 treatment naïve chronic HCV patients with compensated cirrhosis across all major genotypes (GT1-6) for 8wks.
• The P-IIIb EXPEDITION-8 study results: GT1- 6 patients achieving SVR₁₂ (97.7%); GT3 patients achieving SVR₁₂ (95.2%); one case of virologic failure and no case of discontinuation was reported
• Maviret is a combination of NS3/4A protease & NS5A inhibitor and is now available as an 8-week regimen for treatment-naïve- HCV patients without cirrhosis & with compensated cirrhosis- regardless of genotype in the EU

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Ref: AbbVie | Image: AbbVie